NCP Methylene Blue

Type: Vitamins & Supplements
Regular price $75.00
Sale price $75.00 Regular price $87.00
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Pharmaceutical Grade

Precision Dosed

Made in the USA

Compounding Pharmacy Approved

Pack Size
Fast Delivery Manage Subscriptions Anytime

*These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.

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Product Description

☑ Pharmaceutical-Grade.
☑ Precision Dosed.
☑ Made in the USA.

16mg pharmaceutical-grade methylene blue troche. Built by a compounding pharmacy. For people who care about what's actually in what they take.

What's Included:

→ 4 troches per pack 
→ Up to 16 doses per pack 
→ 16mg methylene blue per troche
→ Scored for easy dose titration

Most methylene blue on the market is industrial grade, mislabeled, or sold by people with no clinical background.

Purity matters enormously with this compound.

NCP Methylene Blue is built the way a compounding pharmacy builds things...with pharmaceutical-grade ingredients, precise dosing, and a clinical eye on every detail.

FDA DISCLAIMER:These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

How NCP Methylene Blue Works

Mechanisms of Action

NCP Methylene Blue works at the cellular level through multiple pathways simultaneously:

→ Increases ATP production by donating electrons to Complex IV on the electron transport chain

→ Acts as a powerful antioxidant — accepts electrons to neutralize reactive oxygen species

→ Increases NAD+ production via enhanced glycolysis and NADPH oxidation

→ Mildly increases serotonin, dopamine, and norepinephrine (mild MAO-I activity)

→ Decreases inflammation

What's Included

Built by a compounding pharmacy. For people who care about what's actually in what they take.

→ 16mg pharmaceutical-grade methylene blue per troche
→ 4 troches per pack 
→ Up to 16 doses per pack 
→ Scored for easy dose titration

Product Ingredients

ACTIVE Ingredients:

Methylene Blue — 16mg per troche

INACTIVE Ingredients:

Polyethylene Glycol (PEG)

  • Pharmaceutical-grade suspension base
  • Fully excreted — not absorbed into the body
  • Very low dose (<500mg per troche)
  • FDA-approved drug delivery method used worldwide by compounding pharmacists

Silica — food grade
Bitter Bloc

  • non-GMO,
  • preservative and dye free
  • GRAS status, mushroom-derived

Natural Sweeteners

  • Monk Fruit, Stevia

Flavoring

  • Peppermint

How to Calibrate Your Dose

→ STEP 1 — CHOOSE YOUR STARTING POINT Start with 1/4 to 1/2 troche. Each troche is scored for easy splitting. Your optimal dose is personal — start low and adjust.

→ STEP 2 — FIND THE SWEET SPOT Place the troche between your gum and upper cheek. Alternatively, MB is highly bioavailable and can be swallowed on an empty stomach.

→ STEP 3 — PATIENCE IS KEY Buccal absorption: onset 15–20 minutes. Swallowed on empty stomach: onset 60–90 minutes.

→ STEP 4 — FEEL THE SHIFT Methylene blue works at the mitochondrial level. The effect is clean and sustained — not a spike.

→ STEP 5 — FIND YOUR DOSE Maximum daily dose: 4 troches per 24-hour period. If taking more than 30mg daily, take at least one day off per week. Adults 21 years of age or older, or as directed by a healthcare practitioner.Add your content here.

Adults 21 years of age or older, or as directed by a healthcare practitioner.

Potential Interactions & Side Effects

Consult your healthcare provider before use if you take any of the following:

  1. SSRI or SNRI medications — at our dosing, serious interaction is rare and many clinicians use MB alongside these medications, but only under close supervision.
  2. Antipsychotics
  3. Dopaminergic medications (including those for Parkinson's Disease) If you are taking any medication, consult your healthcare provider before use.

CONTRAINDICATIONS — Do not use if you are:

  1. Pregnant or breastfeeding
  2. Have hepatic or renal impairment
  3. Have any known sensitivity to methylene blue or thiazine dye 

POSSIBLE SIDE EFFECTS:

  1. Blue urine — methylene blue concentrates in urine. This is benign.
  2. Blue tongue and teeth — also benign. May last up to 6 hours or occasionally longer. DO NOT use as a buccal troche if you have plastic veneers or non-porcelain dental appliances. Consult your dentist with any concerns.
  3. Elevated blood pressure — if you have hypertension or prehypertension and are on medications, do NOT take MB without close supervision.
  4. Mild headache — typically resolves after the first few doses. If it persists, reduce your dose or consult your provider.
  5. Numbness or tingling of tongue or cheek — caused by the peppermint. If this occurs, swallow the troche on an empty stomach instead of buccal absorption.
  6. Note on high doses — doses exceeding 1mg/kg (significantly higher than our formula) can lead to GI biofilm disruption, oxidative stress, and gastric ulceration. Our formula is well below this threshold.

Frequently Asked Questions

What's a buccal troche?

A buccal troche is a delivery system that absorbs active ingredients directly into your bloodstream through the tissue in your cheek — bypassing the digestive system entirely. Faster onset. More efficient absorption. The result is a more direct, potent effect compared to traditional tablets or powders.

Will it turn my tongue blue?

Yes, if used as a buccal troche. Discoloration typically lasts 2–6 hours and is completely benign. If you have dental work and are concerned about staining, consult your dentist. See the side effects section above for tips on reducing the blue faster.

Why does it contain polyethylene glycol (PEG)?

PEG is a long-established, FDA-approved drug delivery method used by compounding pharmacists worldwide. Do not confuse it with propylene glycol — that's antifreeze. Our PEG is non-absorbable, very low dose, and does not cause GI distress. It is pharmaceutical grade and fully tested.

How many doses am I getting?

Each pack contains 4 scored troches. Each troche can be quartered, yielding up to 16 doses per pack depending on your personalized dose.

What's the right dose for me?

Start with 1/4 to 1/2 troche. Increase gradually until you find your optimal effect. The troches are scored to make this easy. Maximum: 4 troches per 24-hour period.

Why NCP Methylene Blue

Purity matters enormously with this compound.

NCP Methylene Blue is built the way a compounding pharmacy builds things...with pharmaceutical-grade ingredients, precise dosing, and a clinical eye on every detail.

Most methylene blue on the market is industrial grade, mislabeled, or sold by people with no clinical background.

Download the Certificate of Analysis
Three boxes of North Century Pharmacy Methylene Blue on a gray background

How to Use Methylene Blue